Differential Scanning Calorimeter

TA Instruments DSC 2500
Soft Materials Lab - B606
Primary Training Contact
Operating Procedures

Differential scanning calorimetry is a thermoanalytical technique used to measure the amount of heat released or absorbed by a sample during heating or cooling over a range of temperatures. As well as being used to characterize the thermal properties of a material, a differential scanning calorimeter is used to determine the temperature at which particular phase transitions occur, including glass transition temperature, fusion and crystallization events.

During a change in temperature, DSC measures a heat quantity, which is radiated or absorbed excessively by the sample on the basis of a temperature difference between the sample and a reference material.


DSC is a valuable analytical technique for polymers, organic chemicals, pharmaceuticals, oils and greases, foods and biological materials, as well as metals and some inorganic materials. Typic measurements include:

  • Glass transitions, crystallization, and melting transitions
  • Curing reactions and kinetics of thermosets
  • Oxidative stability of lubricants and polymers
  • Purity of pharmaceuticals and organics
  • Specific heat capacity of materials
  • Catalyst efficiency


Sample types

 The DSC can be used to analyze virtually any material that can be put into a DSC sample pan. This includes:

  • Films
  • Fibers
  • Powders
  • Solutions
  • Composites
  • Fusion Cell™ with patented technology for high performance in baseline flatness, sensitivity, resolution, reproducibility, and reliability.
  • Exclusive T4P Tzero® heat flow technology for ultimate DSC performance and unique capability to conduct and store heat capacity measurements in a single run.
  • Reliable linear autosampler with programmable tray positions for worry-free 24/7 operation, most flexible programming of experiments, and automated calibration and verification routines.
  • Modulated DSC®, (MDSC®), for the most efficient separation of complex thermal events.
  • Wide range of temperature 
  • Tzero Press and Pans for fast, simple, and reproducible sample preparation.



Baseline Flatenss (-50 to 300) ≤ 5μW

Baseline Repeatability ≤ 10μW

Temperature Range -180 C to 725 C

Temp Accuracy ± 0.025 C

Temp Precision ± 0.005 C

Enthalpy Precision ± 0.04%