Shared Materials Instrumentation Facility

Cryo-TEM

SMIF’s state-of-the-art cryo-TEM microscopes allow the analysis of biological samples under cryogenic conditions, enabling the determination of high-resolution 3D structures.

Outreach

SMIF Outreach Team visits classrooms, hosts lab tours, and let kids play with expensive equipment (supervised!). It’s SMIF’s way of showing them how fun and fascinating STEM can be.

Staff

SMIF staff hold expertise across a wide range of fields and will help you with your nano-characterization and fabrication needs.

A variety of lithography, deposition, and etching tools in the SMIF cleanroom enable micro- and nano-scale fabrication of electronics, optics, microfluidics, metamaterials, and more! SMIF can facilitate your research and development fabrication needs.

Characterization

SMIF’s characterization tools help visualize and analyze samples at the micro- and nano-scale. SMIF facilitates investigation of a variety of sample types with a wide array of equipment: SEM, TEM, Mass Spec, Micro-CT, Optical Spectroscopy, AFM, along with Soft Materials and X-ray Characterization Equipment.

The Shared Materials Instrumentation Facility (SMIF) at Duke University is an interdisciplinary, shared resource open to Duke University researchers from all schools and departments—as well as to users from other universities, government laboratories and industry.

CoreResearch Reservations

Publications

Kipp, M. A., L. F. Piccirillo and D. Peters (2025). "High precision selenium isotope analysis using a Nu Sapphire collision–reaction cell MC-ICP-MS." Journal of Analytical Atomic Spectrometry 40(10): 2792–2802

https://doi.org/10.1039/D5JA00247H

Instrument: Mass Spec

Ma, Z., R. Kahan, J. Xia, M. Wu, B. Lu, E. David, Y. He, Y. Chen, J. F. Liu, M. Liu, H. Xu, L. Stempora, N. Abraham, R. Zhong, K. Yang, K. Jin, K. Li, M. Zhang, Q. Wu, A. Barbas, J. Kwun, L. P. Lee, T. J. Huang and E. T. Chambers (2025). "Acoustofluidic system for targeted antibody removal in transplantation: Enabling small-volume therapeutic apheresis." Science Advances 11(36): eady3262

https://doi.org/10.1126/sciadv.ady3262

Instruments: Cleanroom, SEM, TEM

Madhurakkat Perikamana, S. K., V. Kumar, P. Mogha, L. Duncan, N. Angel, A. Tata, S. V. Jabba, S. E. Jordt, P. R. Tata and S. Varghese (2025). "Modeling functional responses to pollutant exposure using modular hydrogel supported vascularized alveolosphere-on-a-chip." Biomaterials Science.

https://doi.org/10.1039/D5BM00552C

Instrument: Cleanroom

Cryo-TEM

Outreach

Staff

Cleanroom

Characterization

Upcoming Events

Cleanroom Safety Class

Publications

SMIF in the News

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