ZetaSizer Ultra Red
Soft Materials Lab - B606
Primary Training Contact

The Zetasizer Ultra Red is an analytical tool for all applications where particle or molecular size and zeta potential analysis are required. It features DLS and ELS modalities.

Light scattering allows the characterization of particulate materials. It is commonly applied to colloidal systems, nanoparticles, and macromolecules in solution or dispersion, to determine particle size, molecular weight, or electrophoretic mobility.

Different methods of light scattering analysis provide a range of useful information about your samples:

1. Dynamic Light Scattering (DLS) measures the size and size distribution of molecules and particles.

2. Electrophoretic Light Scattering (ELS) measures the electrophoretic mobility of particles or molecules in dispersion or solution – this is often converted to a ‘zeta potential’.

  • DLS Analysis
    • Measurement of particle size measurements from 0.3nm to 10μm
  • ELS
    • Measurement of surface charge of suspended particles (Zeta Potential)
  • Able to work with challenging sample types, such as proteins, surfactant solutions, and low solid-content samples
  • Supports use of Low Volume Disposable Capillary Cell for size measurements in sample volumes as low as 3 μL
  • Routine sample investigation such as metallic colloids, metal oxides and pigments
  • Molecular weight using Static Light Scattering at 90°
  • ZS Xplorer software suite for simple and flexible method set-up and data analysis
  • Measurement principle: Non-Invasive Back Scatter (NIBS), Dynamic Light Scattering (90° and 13°) and Multi-Angle Dynamic Light Scattering (MADLS®)
  • Size range: 0.3 nm to 10 μm
  • Minimum volume: 3 μL
  • Concentration range:
    • Minimum: 0.3 mg/mL 15 kDa Protein
    • Maximum: 40% w/v
Zeta Potential:
  • Measurement principle: ELS with M3-PALS and Constant Current Zeta Mode
  • Size range: 3.8 nm to 100 μm
  • Minimum volume: 20 μL
  • Concentration range: 1 mg/mL to 40% w/v
  • Sample conductivity range: maximum of 260 mS/cm
Static Light Scattering (Molecular Weight):
  • Measurement principle: Static light scattering with Debye plot
  • Molecular weight range: 300 Da - 20 MDa
  • Accuracy: +/- 10% typical